A Genetic test for Alopecia and other hair loss
Fagron TrichoTest™ analyzes gene variations and lifestyle factors so that personalized hair loss treatments can be accurately recommended.
Studies show there is a relationship between your genetic profile and how your hair loss responds to
different types of treatment.This means not all hair loss treatments work for everybody and the success of any given treatment is dependent on your genetic profile and lifestyle factors.
Thanks to the unique analysis performed by Fagron TrichoTest™ we can identify which hair loss treatments are most likely to provide the best results for you.
The process is simple and the test can be taken by anyone.
What is alopecia?
Alopecia is a medical term used to describe a dermatological condition characterized by hair loss in the scalp or other areas of the body, for example beard and eyelashes. There are several possible causes of alopecia, such as genetic factors, hormonal dysregulation, auto-immune disorders, or pharmacological treatments.
For decades, research of the treatment of alopecia was focused exclusively on the drug. The physiology of the hair system, which can directly influence treatment efficacy, has not been considered. The hair system is fragile and can be easily affected when exposed to internal and external factors such as inadequate care, environmental pollution and aggressive treatments.
It has been reported that when all parts of the hair follicle are nourished and protected from external aggression, the treatment of alopecia may have a superior result.1 Several products that are currently used in hair formulations, such as alcohol, propylene glycol and some surfactants, can have a negative effect on hair health.
Fagron’s TrichoConcept™ is the first global line of multifunctional compounding vehicles with TrichoTech™ technology, a Fagron patented phytocomplex specially developed for the use in personalized alopecia treatment.
TrichoTech™ and hair growth
Until now, prescribers have had a limited arsenal of vehicles compatible with the Active Pharmaceutical Ingredients (APIs) and Dermaceutical Ingredients (DCIs) used to treat alopecia. In order to provide an answer to this need, Fagron developed the TrichoConcept™ line. All TrichoConcept™ vehicles contain TrichoTech™, Fagron’s patented phytocomplex, extracted from standardized crops of Brazil’s mountains.
The use of phytocomplexes as hair growth stimulants has been considered an effective secondary way for the treatment of hair loss, especially when first-line treatments such as the application of minoxidil or the administration of finasteride result in poor performance or adverse reactions. The vehicles focus on maintaining the physiology of the BSS hair system (Bulb, Scalp and Shaft).
When the physiology of the hair system is appropriate, it becomes more receptive to APIs. An in vitro human fibroblast lineage study by the Research and Development Center of the Institute of Osmology and Essential Oils (IOOE) reported that TrichoTech™ induced the proliferation of the fibroblasts studied, possibly through the upregulation of the MAP kinase signaling pathway, promoting an increase in the cell population in the S-G2-M cell cycle stage and increasing around 25-30 % of the collagen production.
In addition, it was also reported an enhanced cell migration and increased mRNA levels of the FGF-7 and FGF-10 genes.
The clinical efficacy was also evaluated and showed a significant increase of 20% of hair in the anagen phase on the group treated with Minoxidil 3% in TrichoSol™, when compared to the untreated group (p>0.05). This increase was observed for both men and women.
The results suggest that TrichoSol™ acts in synergy with Minoxidil in the neogen phase of the hair cycle.